A 27-year-old man with recurrent episodes of angiooedema since he was 19 responded well to a treatment with cannabis, researchers of the Ben-Gurion University of the Negev in Beersheba, Israel, reported in the journal Case Reports in Immunology. Initially, the patient responded well to steroids and antihistamines, but several attempts to withdraw treatment resulted in recurrence. In the last few months before prescribing cannabis, the frequency and severity of the attacks worsened.
The patient reported that he was periodically using cannabis socially and that during these periods he was free of attacks. Doctors decided to try inhaled cannabis, which resulted in a complete response, and he has been free of symptoms for 2 years. An attempt to withhold the inhaled cannabis led to a recurrent attack within a week. Angiooedema, also known as Quincke’s oedema, is the rapid swelling (oedema) of the skin, subcutaneous tissue, mucosa and submucosal tissues